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1

Quantitative structure–activity relationships for organophosphates binding to acetylcholinesterase

Christopher D. Ruark, C. Eric Hack, Peter J. Robinson, Paul E. Anderson, Jeffery M. Gearhart

Journal:

Archives of Toxicology

Year:

2013

Language:

english

File:

PDF, 355 KB

english, 2013

2

Development and evaluation of a high throughput inhalation model for organic chemicals

Linakis, Matthew W., Sayre, Risa R., Pearce, Robert G., Sfeir, Mark A., Sipes, Nisha S., Pangburn, Heather A., Gearhart, Jeffery M., Wambaugh, John F.

Journal:

Journal of Exposure Science and Environmental Epidemiology

Year:

2020

File:

PDF, 1.53 MB

2020

3

Intermittent exposures to mixed atmospheres of nitrogen dioxide and sulfuric acid: Effect on particle clearance from the respiratory region of rabbit lungs

Richard B. Schlesinger, Jeffery M. Gearhart

Journal:

Year:

1987

Language:

english

File:

PDF, 625 KB

english, 1987

4

Respiratory and metabolic response of rats and mice to formalin vapor

Rudolph J. Jaeger, Jeffery M. Gearhart

Journal:

Year:

1982

Language:

english

File:

PDF, 571 KB

english, 1982

5

Evaluation of the Uncertainty in an Oral Reference Dose for Methylmercury Due to Interindividual Variability in Pharmacokinetics

Harvey J. Clewell, Jeffery M. Gearhart, P. Robinan Gentry, Tammie R. Covington, Cynthia B. VanLandingham, Kenny S. Crump, Annette M. Shipp

Journal:

Year:

1999

Language:

english

File:

PDF, 984 KB

english, 1999

6

Evaluation of the Uncertainty in an Oral Reference Dose for Methylmercury Due to Interindividual Variability in Pharmacokinetics

Harvey J. Clewell, Jeffery M. Gearhart, P. Robinan Gentry, Tammie R. Covington, Cynthia B. VanLandingham, Kenny S. Crump, Annette M. Shipp

Journal:

Year:

1999

Language:

english

File:

PDF, 166 KB

english, 1999

7

Physiologically based pharmacokinetic and pharmacodynamic model for the inhibition of acetylcholinesterase by diisopropyfluorophosphate

Jeffery M. Gearhart, Gary W. Jepson, Harvey J. Clewell III, Melvin E. Andersen, Rory B. Conolly

Journal:

Toxicology and Applied Pharmacology

Year:

1990

Language:

english

File:

PDF, 1.26 MB

english, 1990

8

An agent-based approach to multi-scale neuronal network simulations using modified McCulloch-Pitts neurons

Hanes, Amanda L, Poeppelman, Lee D, Gearhart, Jeffery M

Journal:

BMC Neuroscience

Year:

2012

Language:

english

File:

PDF, 88 KB

english, 2012

9

A Partition Coefficient Determination Method for Nonvolatile Chemicals in Biological Tissues

Gary W. Jepson, David K. Hoover, Richard K. Black, James D. McCafferty, Deirdre A. Mahle, Jeffery M. Gearhart

Journal:

Fundamental and Applied Toxicology

Year:

1994

File:

PDF, 365 KB

1994

10

Quantitative Structure–Activity Relationships for Organophosphates Binding to Trypsin and Chymotrypsin

Ruark, Christopher D., Hack, C. Eric, Robinson, Peter J., Gearhart, Jeffery M.

Journal:

Journal of Toxicology and Environmental Health

Year:

2010

Language:

english

File:

PDF, 1.76 MB

english, 2010

11

Lactational Transfer of Volatile Chemicals in Breast Milk

Fisher, Jeffrey, Mahle, Deirdre, Bankston, Laurie, Greene, Robert, Gearhart, Jeffery

Journal:

Year:

1997

Language:

english

File:

PDF, 834 KB

english, 1997

12

Protection against paraoxon toxicity by an intravenous pretreatment with polyethylene-glycol-conjugated recombinant butyrylcholinesterase in macaques

Rosenberg, Yvonne J., Gearhart, Jeffery, Mao, Lingjun, Jiang, Xiaoming, Hernandez-Abanto, Segundo

Journal:

Chemico-Biological Interactions

Year:

2014

Language:

english

File:

PDF, 455 KB

english, 2014

13

Sulfuric Acid-Induced Changes in the Physiology and Structure of the Tracheobronchial Airways

Jeffery M. Gearhart and Richard B. Schlesinger

Journal:

Environmental Health Perspectives

Year:

1989

Language:

english

File:

PDF, 2.15 MB

english, 1989

14

Proposed PBPK Model to Predict Infant Exposure: Clewell and Gearhart's Response

Rebecca A. Clewell and Jeffery M. Gearhart

Journal:

Environmental Health Perspectives

Year:

2002

Language:

english

File:

PDF, 556 KB

english, 2002

15

Supplement 2: Trichloroethylene Health Risks-State of the Science || Development of a Physiologically Based Pharmacokinetic Model of Trichloroethylene and Its Metabolites for Use in Risk Assessment

Harvey J. Clewell III, P. Robinan Gentry, Tammie R. Covington and Jeffery M. Gearhart

Journal:

Environmental Health Perspectives

Year:

2000

Language:

english

File:

PDF, 4.85 MB

english, 2000

16

Predicting Passive and Active Tissue:Plasma Partition Coefficients: Interindividual and Interspecies Variability

Ruark, Christopher D., Hack, C. Eric, Robinson, Peter J., Mahle, Deirdre A., Gearhart, Jeffery M.

Journal:

Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 6.84 MB

english, 2014

17

Pharmacokinetics of Toxic Chemicals in Breast Milk: Use of PBPK Models to Predict Infant Exposure

Rebecca A. Clewell and Jeffery M. Gearhart

Journal:

Environmental Health Perspectives

Year:

2002

Language:

english

File:

PDF, 2.04 MB

english, 2002

18

A Partition Coefficient Determination Method for Nonvolatile Chemicals in Biological Tissues

JEPSON, GARY W., BLACK, RICHARD K., MCCAFFERTY, JAMES D., MAHLE, DEIRDRE A., GEARHART, JEFFERY M.

Journal:

Toxicological Sciences

Year:

1994

Language:

english

File:

PDF, 550 KB

english, 1994

19

Quantitative proteomic analysis of the brainstem following lethal sarin exposure

Meade, Mitchell L., Hoffmann, Andrea, Makley, Meghan K., Snider, Thomas H., Schlager, John J., Gearhart, Jeffery M.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.89 MB

english, 2015

20

Potential new therapeutic modality revealed through agent-based modeling of the neuromuscular junction and acetylcholinesterase inhibition

Chapleau, Richard R, Robinson, Peter J, Schlager, John J, Gearhart, Jeffery M

Journal:

Theoretical Biology and Medical Modelling

Year:

2014

Language:

english

File:

PDF, 949 KB

english, 2014

21

Evidence for Competitive Inhibition of Iodide Uptake by Perchlorate and Translocation of Perchlorate into the Thyroid

Clewell, Rebecca, Merrill, Elaine, Narayanan, Latha, Gearhart, Jeffery, Robinson, Peter

Journal:

International Journal of Toxicology

Year:

2004

Language:

english

File:

PDF, 150 KB

english, 2004

22

Perchlorate and Radioiodide Kinetics Across Life Stages in the Human: Using PBPK Models to Predict Dosimetry and Thyroid Inhibition and Sensitive Subpopulations Based on Developmental Stage

Clewell, Rebecca A., Merrill, Elaine A., Gearhart, Jeffery M., Robinson, Peter J., Sterner, Teresa R., Mattie, David R., Clewell, Harvey J.

Journal:

Journal of Toxicology and Environmental Health

Year:

2007

Language:

english

File:

PDF, 796 KB

english, 2007

23

Age-Dependent Partition Coefficients for a Mixture of Volatile Organic Solvents in Sprague-Dawley Rats and Humans

Mahle, Deirdre A., Gearhart, Jeffery M., Grigsby, Claude C., Mattie, David R., Barton, Hugh A., Lipscomb, John C., Cook, Robert S.

Journal:

Journal of Toxicology and Environmental Health

Year:

2007

Language:

english

File:

PDF, 78 KB

english, 2007

24

Handbook of Toxicology of Chemical Warfare Agents || Physiologically Based Pharmacokinetic Modeling of Chemical Warfare Agents

Gearhart, Jeffery M.

Year:

2015

Language:

english

File:

PDF, 918 KB

english, 2015

25

INVESTIGATION OF THE POTENTIAL IMPACT OF BENCHMARK DOSE AND PHARMACOKINETIC MODELING IN NONCANCER RISK ASSESSMENT

Clewell Iii, Harvey J., Gentry, P. Robinan, Gearhart, Jeffery M.

Journal:

Journal of Toxicology and Environmental Health

Year:

1997

Language:

english

File:

PDF, 1.17 MB

english, 1997

26

Sulfuric Acid-Induced Airway Hyperresponsiveness

GEARHART, JEFFERY M., SCHLESINGER, RICHARD B.

Journal:

Toxicological Sciences

Year:

1986

Language:

english

File:

PDF, 661 KB

english, 1986

27

INVESTIGATION OF THE POTENTIAL IMPACT OF BENCHMARK DOSE AND PHARMACOKINETIC MODELING IN NONCANCER RISK ASSESSMENT

Clewell, Harvey, Gentry, P. Robinan, Gearhart, Jeffery

Journal:

Journal of Toxicology and Environmental Health

Year:

1997

Language:

english

File:

PDF, 1.35 MB

english, 1997

28

Early alveolar clearance in rabbits intermittently exposed to sulfuric acid mist

Schlesinger, Richard B., Gearhart, Jeffery M.

Journal:

Journal of Toxicology and Environmental Health

Year:

1986

Language:

english

File:

PDF, 652 KB

english, 1986

29

Response of the Tracheobronchial Mucociliary Clearance System to Repeated Irritant Exposure: Effect of Sulfuric Acid Mist on Function and Structure

Gearhart, Jeffery M., Schlesinger, Richard B.

Journal:

Experimental Lung Research

Year:

1988

Language:

english

File:

PDF, 1.28 MB

english, 1988

30

A Rabbit Lung Morphology Model for Aerosol Deposition and Clearance

Hack, C.Eric, Gearhart, Jeffery M.

Journal:

Journal of Aerosol Science

Year:

2016

Language:

english

File:

PDF, 1.31 MB

english, 2016

31

Supplement 11: Dosimetry for Risk Assessment || Physiologically Based Pharmacokinetic Model for the Inhibition of Acetylcholinesterase by Organophosphate Esters

Jeffery M. Gearhart, Gary W. Jepson, Harvey J. Clewell, Melvin E. Andersen and Rory B. Conolly

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 2.25 MB

english, 1994

32

Predicting neurological targets for chemical neurotoxins using ToxCast in vitro data and read-across within QSAR Toolbox

Chushak, Yaroslav, Pangburn, Heather, Gearhart, Jeffery M.

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 57 KB

english, 2017

33

Development of a Physiologically Based Model to Describe the Pharmacokinetics of Methylphenidate in Juvenile and Adult Humans and Nonhuman Primates

Yang, Xiaoxia, Morris, Suzanne M., Gearhart, Jeffery M., Ruark, Christopher D., Paule, Merle G., Slikker, William, Mattison, Donald R., Vitiello, Benedetto, Twaddle, Nathan C., Doerge, Daniel R., Youn

Journal:

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

34

Broad spectrum proteomics analysis of the inferior colliculus following acute hydrogen sulfide exposure

Kim, Dong-Suk, Anantharam, Poojya, Hoffmann, Andrea, Meade, Mitchell L., Grobe, Nadja, Gearhart, Jeffery M., Whitley, Elizabeth M., Mahama, Belinda, Rumbeiha, Wilson K.

Journal:

Toxicology and Applied Pharmacology

Year:

2018

Language:

english

File:

PDF, 4.12 MB

english, 2018

35

Inhalational anthrax (Ames aerosol) in naïve and vaccinated New Zealand rabbits: characterizing the spread of bacteria from lung deposition to bacteremia

Gutting, Bradford W., Nichols, Tonya L., Channel, Stephen R., Gearhart, Jeffery M., Andrews, George A., Berger, Alan E., Mackie, Ryan S., Watson, Brent J., Taft, Sarah C., Overheim, Katie A., Sherwood

Journal:

Frontiers in Cellular and Infection Microbiology

Year:

2012

Language:

english

File:

PDF, 531 KB

english, 2012

36

Basis for a particle size-selective TLV for sulfuric acid aerosols

Lippmann, Morton, Gearhart, Jeffery M., Schlesinger, Richard B.

Journal:

Applied Industrial Hygiene

Year:

1987

Language:

english

File:

PDF, 1.36 MB

english, 1987

37

Considerations for Development of Exposure Limits for Chemicals Encountered During Aircraft Operation

Sweeney, Lisa M, Gearhart, Jeffery M, Ott, Darrin K, Pangburn, Heather A

Journal:

Military Medicine

Year:

2020

Language:

english

File:

PDF, 484 KB

english, 2020

38

Handbook of Toxicology of Chemical Warfare Agents || Physiologically Based Pharmacokinetic Modeling of Chemical Warfare Agents

Gearhart, Jeffery M.

Year:

2009

File:

PDF, 588 KB

2009

39

Handbook of Toxicology of Chemical Warfare Agents || Physiologically based pharmacokinetic modeling of chemical warfare agents

Gearhart, Jeffery M.

Year:

2020

File:

PDF, 906 KB

2020

40

Correction: Development and evaluation of a high throughput inhalation model for organic chemicals

Linakis, Matthew W., Sayre, Risa R., Pearce, Robert G., Sfeir, Mark A., Sipes, Nisha S., Pangburn, Heather A., Gearhart, Jeffery M., Wambaugh, John F.

Journal:

Journal of Exposure Science and Environmental Epidemiology

Year:

2020

File:

PDF, 179 KB

2020

41

In Silico Assessment of Acute Oral Toxicity for Mixtures

Chushak, Yaroslav, Gearhart, Jeffery M., Ott, Darrin

Journal:

Chemical Research in Toxicology

Year:

2020

File:

PDF, 2.37 MB

2020

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